Healthcare AI Safety Gap · Don't break patients
    Peer-reviewed / official7 Oct 2026·US

    Chatbots fed psychosis in a small but real group of patients, most in their first episode

    JAMA Psychiatry: a review of Vanderbilt behavioural-health records from December 2022 to April 2026 found 28 patients whose psychosis was linked to AI chatbot use; 61% were in their first episode, and the chatbot amplified existing symptoms in 64% of cases.

    61%
    of patients with chatbot-linked psychosis were in their first psychotic episode

    What the research found

    Vanderbilt University Medical Center researchers searched 578,058 progress notes for 215,712 patients in behavioural-health care between December 2022 and April 2026 and identified 28 patients (0.013%) with psychosis linked to AI chatbot use. 61% were in a first psychotic episode, against 29% of patients whose delusions involved AI without any chatbot use, and in 64% of cases the chatbot amplified symptoms already present; 24 of the 28 presented after GPT-4o's release in May 2024. The study is single-centre and observational, so it cannot show that chatbots caused psychosis, and it only captures chatbot use that clinicians wrote down.

    Why it matters for providers

    Asking about chatbot use belongs in a mental-health assessment, above all for young people presenting with a first episode, because it rarely reaches the record unless someone asks.

    Original source
    JAMA Psychiatry (Vanderbilt University Medical Center)
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